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Whether this reflects a true null effect, or whether NAC takes longer to work, as suggested by the two initial studies (6 months) and the Brieier study in schizophrenia (9 months), remains to be determined

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Other components in this family, including BMPR2 (FDR q-value = 0.125) and SMAD7 (FDR q-value = 0.223), also showed evidence of modest down-regulation while SMAD1 showed evidence of modest up-regulation (FDR q-value = 0.101)

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